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Pigmented basal cell carcinoma mimicking nodular melanoma.
BMJ Case Rep
September 2024
Department of Pathology, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.
Article Synopsis
- Basal cell carcinoma (BCC) is the most common type of primary skin cancer, with pigmented BCC being a rare variant that can resemble nodular melanoma (NM).
- A case is presented involving a 40-something woman with a hyperpigmented nodule on her cheek that looked like pigmented NM, but dermoscopy revealed distinct features.
- After initial biopsy showed signs of trichoepithelioma, complete excision confirmed it was pigmented BCC; awareness of this rare presentation is essential for proper diagnosis and management, especially in dark-skinned patients.
Does Immunohistochemistry Add to Morphology in Differentiating Trichoepithelioma, Desmoplastic Trichoepithelioma, Morpheaform Basal Cell Carcinoma, and Microcystic Adnexal Carcinoma?
Appl Immunohistochem Mol Morphol
April 2022
Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center.
Background: The distinction among cutaneous basaloid neoplasms such as trichoepithelioma (TE), desmoplastic trichoepithelioma (DTE), morpheaform basal cell carcinoma (MBCC), and microcystic adnexal carcinoma (MAC) can be difficult, especially in superficial biopsies. As the treatment plan of each entity is different, accurate characterization is important for appropriate management. While TE and DTE are benign neoplasms with indolent behavior, MBCC and MAC are typically locally aggressive.
View Article and Find Full Text PDFMetastatic Spiradenocarcinoma Managed With PD-1 Inhibition.
J Natl Compr Canc Netw
February 2022
Division of Medical Oncology, The Ohio State University James Cancer Hospital, Columbus, Ohio.
Spiradenomas are rare skin adnexal tumors, usually benign, appearing in early adulthood. The etiology of this tumor is still debated. The tumor suppressor gene CYLD, responsible for the Brooke-Spiegler syndrome, causes spiradenomas, trichoepitheliomas, and cylindromas.
View Article and Find Full Text PDFImplication of wide surgical excision in minimizing positive margins and consequential secondary excision - a retrospective comparative study involving 106 basal cell carcinoma cases.
Eur Rev Med Pharmacol Sci
June 2021
Department of Functional Sciences, Physiology, Centre of Immuno-Physiology and Biotechnologies (CIFBIOTEH), "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Objective: The use of current surgical techniques in the management of skin cancers that are not amenable to other treatment options has become the cornerstone of dermatological surgical intervention. Among the many benign lesions and malignant lesions, such as squamous cell carcinomas, melanomas, and Merkel cell carcinomas, the tumors that are commonly excised surgically are the basal cell carcinomas (BCC). Although the majority of BCC lesions spread locally and are rarely metastatic, these lesions may recur, especially, if the excised tissue consists of positive surgical margins.
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