Zinc counteracts experimentally-induced cirrhotic changes in rats.

Indian J Physiol Pharmacol

Institute of Physiology and Experimental Medicine, Madras Medical College.

Published: April 1993

In the present study, cirrhosis was induced in rats by administration of carbon tetra chloride for 8 weeks. In these animals ZnSo4 (equivalent to 100 and 200 micrograms of zinc) was administered orally and liver function tests and plasma zinc (Zn) estimations were carried out after 2 and 4 week intervals. The results revealed that Zn supplement counteracts cirrhotic changes in liver.

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