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Advances and applications of peripheral optogenetics in animal models.
Neuroscience
January 2025
CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China. Electronic address:
Peripheral optogenetics is an emerging neuromodulation technique that regulates the activity of the nervous system outside the brain through the expression of photosensitive proteins and the application of photic stimulation. This article reviews recent advances in applying optogenetics to the spinal cord and peripheral nerves, offering a comprehensive understanding of functions and regulatory mechanisms of the peripheral nervous system through the modulation of specific neuronal activities. By showcasing novel opportunities for disease treatment, this technique opens new avenues in the field of psychophysiological research and neural regulation therapy.
View Article and Find Full Text PDFIndividual Rumination in Adult Cancer Care: A Concept Analysis.
Semin Oncol Nurs
January 2025
School of Nursing, Midwifery and Health Systems, University College Dublin (UCD), Dublin, Ireland.
Objective: To conceptualize rumination in adult cancer care.
Methods: Walker and Avant's concept analysis method was used to examine rumination in adults with cancer. A systematic search was conducted across psychology, nursing, medicine, and public health disciplines in PsycINFO, PubMed, Web of Science, CINAHL, and Scopus databases from their inception to April 2024.
Sex differences in the reactivity of gastric myoelectrical activity and heart rate variability as putative psychophysiological markers in human pain research.
Front Neurosci
December 2024
Department of Neurology, Center for Translational Neuro-and Behavioral Sciences (C-TNBS), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Background: This study explored the potential of electrogastrography (EGG) and heart rate variability (HRV) as psychophysiological markers in experimental pain research related to the gut-brain axis. We investigated responses to the experience of pain from the visceral (rectal distension) and somatic (cutaneous heat) pain modalities, with a focus on elucidating sex differences in EGG and HRV responses.
Methods: In a sample of healthy volunteers (29 males, 43 females), EGG and ECG data were collected during a baseline and a pain phase.
Amygdala-centered emotional processing in Prolonged Grief Disorder: Relationship with clinical symptomatology.
Biol Psychiatry Cogn Neurosci Neuroimaging
December 2024
Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address:
Background: Prolonged Grief Disorder is a multidimensional condition with adverse health consequences. We hypothesized that enhanced negative emotional bias characterizes this disorder and underlies its key clinical symptoms.
Methods: In a cross-sectional design, chronically grieving older adults (61.
Fear and safety learning in anxiety- and stress-related disorders: An updated meta-analysis.
Neurosci Biobehav Rev
December 2024
Department of Psychology, University Hamburg, Hamburg, Germany.
Fear learning processes are believed to play a crucial role in the development and maintenance of anxiety and stress-related disorders. To integrate results across different studies, we conducted a systematic meta-analysis following PRISMA guidelines to examine differences in fear conditioning during fear acquisition, extinction, and extinction recall between individuals with anxiety-related or stress-related disorders and healthy participants. This analysis updates the work of Duits et al.
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