Objective: To establish the predictive role of preovulatory ovarian ultrasonography in the occurrence of multiple pregnancy after hMG and hCG treatment for anovulatory infertility.
Design: Prospective.
Setting: Outpatient Infertility Clinic.
Patients: Ninety-five anovulatory women who conceived after gonadotropin therapy.
Intervention: Induction of ovulation by hMG and hCG monitored by plasma E2 measurements and ovarian ultrasonography.
Main Outcome Measures: All follicles visualized on the day of hCG administration were recorded and divided into the following four groups: group I, 10 to 12 mm; group II, 13 to 15 mm; group III, 16 to 18 mm; and group IV, 19 mm and larger. The sonographic findings were statistically evaluated to 80 singletons and 45 multiple pregnancies.
Results: No statistical correlation was found to exist between the number of follicles from the different groups and the number of fetuses.
Conclusions: The number and sizes of follicles visualized on the day of hCG administration have no predictive value regarding the occurrence of a multiple pregnancy.
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