The political economy framework is presented as a guide to investigate pharmaceutical marketing channels. Based on the framework, pharmaceutical marketing channels are conceptualized as four interacting areas: the environment, the economy, the policy, and the performance of the channel. Examples of this approach are illustrated. The usefulness of the framework for future research and management of pharmaceutical marketing channels is discussed, and strengths and weaknesses are identified.
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AAPS PharmSciTech
January 2025
School of Engineering and Sciences, Tecnologico de Monterrey, Campus Monterrey, Ave. Eugenio Garza Sada 2501 Sur, C.P. 64849, Monterrey, N.L., Mexico.
Metabolic syndrome (MS) has a high prevalence, with an estimated one-quarter of the world population affected by this pathological condition. Among the diseases of this syndrome are dysregulation of lipids, hypertension, and insulin resistance. Unfortunately, available drugs in the market used for treating MS, as almost 75% of all drugs, are highly insoluble, presenting a significant demand for strategies to increase their solubility.
View Article and Find Full Text PDFNo Shinkei Geka
January 2025
Spine Center, Aichi Medical University Hospital.
In Japan, cervical artificial disc replacement was approved by the Pharmaceuticals and Medical Devices Agency in December 2017, and two products, Mobi-C by Zimmer Biomet and Prestige LP by Medtronic, are on the market. Cervical artificial disc replacement preserves cervical motion; however, the device must be place carefully on the midline to take full advantage of its features. In addition, a reliable foraminotomy is required to cure or prevent radiculopathy due to residual foraminal stenosis.
View Article and Find Full Text PDFHum Exp Toxicol
January 2025
AnaPath Services GmbH/K. Weber Consulting GmbH, Oberbuchsiten, Switzerland.
Managing conflicts of interest (COIs) in scientific decision-making is important for minimizing bias and fostering public trust in science. Proper management of COIs has added significance when scientists are making decisions that impact public policy, such as assessing substances for carcinogenicity. The International Agency for Research on Cancer (IARC) organizes expert working groups to identify putative carcinogens and determine whether or not the hazard is likely to present significant potential harm to humans.
View Article and Find Full Text PDFAnal Biochem
January 2025
Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India. Electronic address:
Aptamers, discovered in the 1990s, have marked a significant milestone in the fields of therapeutics and diagnostics. This review provides a comprehensive survey of aptamers, focusing on their diagnostic applications. It especially encapsulates a decade of aptamer, encompassing research, patents, and market trends.
View Article and Find Full Text PDFFood Chem
January 2025
State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China. Electronic address:
Stingless bee honey (SBH) has garnered attention as a natural sweetener and functional food, recognized for its exceptional biological activity and distinctive flavour. Compared to honey bee honey, SBH has lower annual production but commands a higher market value, making it more susceptible to adulteration. During an analysis of trehalulose in SBH, we unexpectedly identified the naturally occurring sugar alcohol, mannitol.
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