A device enabling to expose small laboratory animals (rabbits, cats, etc.) to sea sickness using the swing with one suspended bar in an automatic mode both in horizontal and head-down position with different tilt angles has been developed. The device can be used for affecting during unlimited periods of time the otolith apparatus and semicircular canals in combination, if need be, with antiorthostatic hypokinesia. The design provides quick and easy installation of the container with an animal in horizontal or head-down position.
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J Cardiothorac Vasc Anesth
January 2025
Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology, Moscow, Russia.
Objective: To systematically evaluate the impact of the Trendelenburg position on hemodynamic parameters in adult patients.
Design: Systematic literature review and meta-analysis using PubMed and Medline.
Setting: All prospective interventional studies comparing the hemodynamic characteristics of patients in the horizontal supine position and Trendelenburg position.
Exp Physiol
September 2024
Department of Social Medicine, Division of Hygiene, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
Astronauts experience combined exposure to a cephalad fluid shift and mild hypercapnia during space missions, potentially contributing to health problems. Such combined exposure may weaken dynamic cerebral autoregulation. The magnitude of cephalad fluid shift varies between individuals, and dynamic cerebral autoregulation may be affected more by greater cephalad fluid shift during combined exposure.
View Article and Find Full Text PDFExp Physiol
August 2024
Aerospace Medicine and Rehabilitation Laboratory, Department of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP. We examined LOP at the leg and arm during supine bedrest and bodyweight suspension (BWS) at 6° head-down tilt (HDT), horizontal (0°), and 9.
View Article and Find Full Text PDFSci Rep
March 2024
The Interface Group, Institute of Physiology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
The capacitive measurement of the head's dielectric properties has been recently proposed as a noninvasive method for deriving surrogates of craniospinal compliance (CC), a parameter used in the evaluation of space-occupying neurological disorders. With the higher prevalence of such disorders in the older compared to the younger population, data on the head's dielectric properties of older healthy individuals would be of particularly high value before assessing pathologic changes. However, so far only measurements on young volunteers (< 30 years) were reported.
View Article and Find Full Text PDFBrain Res
December 2023
Independent Researcher, Lithuania. Electronic address:
Evolutionary cerebrovascular consequences of upside-down postural verticality of the anthropoid fetus have been largely overlooked in the literature. This working hypothesis-based report provides a literature interpretation from an aspect that the rapid evolution of the human brain has been promoted by fetal head-down position due to maternal upright and semi-upright posture. Habitual vertical torso posture is a feature not only of humans, but also of monkeys and non-human apes that spend considerable time in a sitting position.
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