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Smoking and contraception containing ethinylestradiol: A mixed-methods study into women's intentions to quit smoking.
Womens Health (Lond)
December 2024
Student Health Service, University of Amsterdam, Amsterdam, The Netherlands.
Background: Smoking while using contraception containing ethinylestradiol increases the risk of cardiovascular diseases. Therefore, it is especially important to stimulate women who use these contraceptives to quit smoking.
Objectives: This study aimed to examine the role of risk perception and coping in relation to the intention of these women to quit smoking, using the Protection Motivation Theory as the theoretical foundation.
Coupling UiO-66 MOF with a Nanotubular Oxide Layer Grown on Ti-W Alloy Accelerates the Degradation of Hormones in Real Water Matrices.
ACS Omega
December 2024
Department of Chemical Engineering, Instituto de Ciências Ambientais, Químicas Farmacêuticas, Universidade Federal de São Paulo, Rua São Nicolau, 210, Diadema, Sao Paulo 09913-030, Brazil.
To enable the photoelectrocatalytic treatment of large volumes of water containing low concentrations of pollutants, this study introduces a hybrid photocatalyst, composed of nanotubular oxides grown on TiW alloy ( = 0.5 and 5.0 wt %) modified with UiO-66 MOF, for degradation of estrone (E1) and 17α-ethinyl estradiol (EE2).
View Article and Find Full Text PDFOvulation sources ROS to confer mutagenic activities on the TP53 gene in the fallopian tube epithelium.
Neoplasia
January 2025
Center for Prevention and Therapy of Gynecological Cancers, Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, ROC; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan, ROC; Department of Obstetrics & Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, ROC. Electronic address:
Introduction: Epidemiological studies have implicated ovulation as a risk factor for ovarian high-grade serous carcinoma (HGSC) at the initiation stage. Precancerous lesions of HGSC commonly exhibit TP53 mutations attributed to DNA deamination and are frequently localized in the fallopian tube epithelium (FTE), a site regularly exposed to ovulatory follicular fluid (FF). This study aimed to assess the mutagenic potential of FF and investigate the expression levels and functional role of activation-induced cytidine deaminase (AID) following ovulation, along with the resulting TP53 DNA deamination.
View Article and Find Full Text PDFProgesterone treatment is not necessary for sexual experience-enhanced paced mating behavior in estradiol benzoate-primed female rats.
Behav Neurosci
February 2025
Department of Psychology, Neuroscience Program, Carleton College.
Article Synopsis
- Sexual behavior in female rats is affected by their sexual history and the type of ovarian hormones used to promote receptivity.
- Experiment 1 found that rats with experience under the hormone combination of estradiol benzoate and progesterone (EB/P) were more motivated to mate compared to those treated only with estradiol benzoate (EB).
- Experiment 2 demonstrated that sexually experienced rats show improved paced mating behaviors with both hormone treatments, but those primed with EB alone displayed lower sexual motivation and engagement compared to those primed with EB/P, highlighting the role of progesterone in enhancing mating behavior.
- Overall, the study suggests that previous sexual experience improves mating behavior, but the presence of progesterone significantly boosts this motivation.
Cellular and molecular mechanisms of action of ovarian steroid hormones II: Regulation of sexual behavior in female rodents.
Neurosci Biobehav Rev
January 2025
Centro de Investigación de Investigación en Reproducción Animal, Universidad Autónoma de Tlaxcala-CINVESTAV, Tlaxcala, México. Electronic address:
Female sexual behaviors in rodents (lordosis and appetitive or "proceptive" behaviors) are induced through a genomic mechanism by the sequential actions of estradiol (E2) and progesterone (P), or E2 and testosterone (T) at their respective receptors. However, non-steroidal agents, such as gonadotropin-releasing hormone (GnRH), Prostaglandin E2 (PGE2), noradrenaline, dopamine, oxytocin, α-melanocyte stimulating hormone, nitric oxide, leptin, apelin, and others, facilitate different aspects of female sexual behavior through their cellular and intracellular effects at the membrane and genomic levels in ovariectomized rats primed with E2. These neurotransmitters often act as intermediaries of E2 and P (or T).
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