For obtaining a better yield of established lines of embryonic Drosophila cells, insulin proved to be a useful substance to be added to the culture medium. 10% of lines became established, showing a predominantly diploid chromosome number.
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Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation.
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Adaptation to existence outside the womb is a key event in the life of a mammal. The absence of macrophages in rats with a homozygous mutation in the colony-stimulating factor 1 receptor (Csf1r) gene (Csf1rko) severely compromises pre-weaning somatic growth and maturation of organ function. Transfer of wild-type bone marrow cells (BMT) at weaning rescues tissue macrophage populations permitting normal development and long-term survival.
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Statoliths function in gravity perception in plants: yes, no, yes!
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