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Ace-1 Target Site Status and Metabolic Detoxification Associated with Bendiocarb Resistance in the Field Populations of Main Malaria Vector, in Iran.
J Arthropod Borne Dis
September 2023
Department of Vector Biology and Control of Diseases, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Background: is the main vector of malaria in Iran. This study aimed to determine the susceptibility of from the south of Iran to bendiocarb and to investigate biochemical and molecular resistance mechanisms in this species.
Methods: Wild were collected from Hormozgan Province and reared to the adult stage.
A mutation panel comprising BRAF, NRAS, and NRAS replicated retrospective histopathological examination findings in differentiating benign goitre from malignant papillary thyroid cancer in a cohort of Malaysian patients.
Malays J Pathol
December 2023
Universiti Malaya, Faculty of Medicine, Department of Molecular Medicine, 50603 Kuala Lumpur, Malaysia.
Thyroid malignancy status is usually confirmed through histopathological examination (HPE) following thyroidectomy. In Malaysia, the application of molecular markers in pre-operative diagnosis of thyroid cancer remains unexplored. In this study, BRAF and NRAS gene mutation panel was assessed, and the results were compared with retrospective HPE findings.
View Article and Find Full Text PDFA practical workflow for forensic species identification using direct sequencing of real-time PCR products.
Mol Biol Rep
December 2023
Department of Legal Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.
Background: Forensic scientists are often required to identify species of unknown biological samples. Although methods based on sequencing of DNA barcode regions are the gold standard for species identification in single-source forensic samples, they are cumbersome to implement as routine work in forensic laboratories that perform many tests, including human DNA typing. We have developed a species identification workflow that incorporates direct sequencing with real-time PCR products (real-time PCR-direct sequencing) as the technical trick for easy testing in forensic practice.
View Article and Find Full Text PDFMolecular characteristics of hereditary red blood cell membrane disorders in Thailand: a multi-center registry.
Ann Hematol
February 2024
Thalassemia and Hematology Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Red blood cell (RBC) membrane disorders represent a significant category of hereditary hemolytic anemia; however, information from Southeast Asia is limited. We established a national registry aiming to characterize RBC membrane disorders and their molecular features in Thailand. A total of 100 patients (99 kindreds) diagnosed with RBC membrane disorders between 2011 and 2020 from seven university hospitals were enrolled.
View Article and Find Full Text PDFPrevalence of in High-Risk Human Papillomavirus-Positive Women: A Study in Diyarbakır Province, Turkey.
Can J Infect Dis Med Microbiol
October 2023
Department of Gyneacological Oncology, Gazi Yaşargil Training and Research Hospital, Diyarbakir, Turkey.
The human papillomavirus (HPV) is a significant public health concern due to its association with the development of cervical cancer. Although inflammation caused by spp. has been shown to facilitate oncogenesis, the interactions between HPV and spp.
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