Chronic fistula of total gastric pouch in Rat, until now unsuccessfully performed, is realizable. It provided a pure gastric juice and solved the reproducibility of the results. Quantity of daily secretion juice was variable from one animal to another, but remained constant for the same animal; it influenced the evolution of the animal state; the larger it was the less likely the operated animal was to survive. Many of our animals are now 3 months old; they are well, in spite of a 20% loss of body weight since the operation.
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