Objective: A study was performed to determine reference ranges for whole body plethysmographic gas volumes and single breath gas transfer in healthy prepubertal and pubertal schoolchildren.
Methods: The study was performed in 772 white London schoolchildren (455 male) who were clinically examined, assessed auxologically and, in 63% of cases, pubertally staged. Regression equations for the calculation of standard deviation scores were derived.
Results: Male lung function variables showed a discontinuous pattern of increase with standing height. Linear increases until puberty were followed by a sudden pubertal rise and a further increase with height which was more marked than before puberty. Correction for varying thoracic dimensions eliminated these changes. In females a smoother curvilinear relationship was observed with no correction possible for thoracic size.
Conclusions: Male puberty leads to profound changes in pulmonary function mostly related to thoracic size, an effect not observed in females.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC464705 | PMC |
| http://dx.doi.org/10.1136/thx.48.8.803 | DOI Listing |
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