64 patients with infectious-allergic bronchial asthma (IABA) were examined. 20 of them were co-administered paspat, 24 patients additionally received prodigiosan, 20 patients constituted control group and were given conventional treatment. Patients of all the groups were comparable in age, state of immunological reactivity of the body and severity of the disease. Immunomodulatory effect of the drugs, mainly of paspat, not only resulted in normalization of functional properties of granulocytes but also promoted liquidation of quantitative and functional IABA-conditioned immunodeficiency on the part of T- and B-lymphocytes, thus increasing effectiveness of the treatment in the whole.
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Klin Lab Diagn
January 2017
The diagnostic center (Center of laboratory studies) of he Moscow health department, 115580, Moscow, Russia.
The fungi genus Paecilomyces are spread everywhere in nature. They attract attention from the middle of 1960s as a cause of development of septic endocarditis, sepsis, pneumonia and other types of pathology developed against the background of immunodeficiency. They induce development of infectious allergic alveolitis and bronchial asthma.
View Article and Find Full Text PDFAllergy
April 2013
Department of Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland.
Extracellular DNA traps are part of the innate immune response and are seen with many infectious, allergic, and autoimmune diseases. They can be generated by several different leukocytes, including neutrophils, eosinophils, and monocytes, as well as mast cells. Here, we review the composition of these extracellular DNA-containing structures as well as potential mechanisms for their production and function.
View Article and Find Full Text PDFClin Chest Med
March 2010
Firestone Institute for Respiratory Health, St Joseph's Healthcare Hamilton, 50 Charlton Avenue E, Hamilton, ON L8N 4A6, Canada.
Asthma, by definition is a variable disease. When there is more than normal natural variation in airflow, asthma can be provoked by a wide range of stimuli that include infectious, allergic, and environmental agents. Bronchoconstriction determines much of the short-term variability in airflow that characterizes asthma.
View Article and Find Full Text PDFIn 7 patients aged from 43 to 64 years with severe infectious allergic forms of bronchial asthma with curative aims radiofrequency electrostimulator for the boundary trunk of the sympathic nerve (BTSN) has been implanted in the neck. Daily sessions of electrostimulation (ES) by the current with parameters 1-100 Hz, 0.1-0.
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