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| http://dx.doi.org/10.1136/pgmj.69.812.497-a | DOI Listing |
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Olanzapine induced Q-Tc shortening.
Ther Adv Psychopharmacol
December 2014
Internal Ward, Razi Psychiatric Hospital, Tehran, Iran.
Introduction: Prolongation of Q-Tc interval is commonly accepted as a surrogate marker for the ability of a drug to cause torsade de pointes. In the present study, safety of olanzapine versus risperidone was compared among a group of patients with schizophrenia to see the frequency of the electrocardiographic alterations induced by those atypical antipsychotics.
Method: Two hundred and sixty-eight female inpatients with schizophrenia entered in one of the two parallel groups to participate in an open study for random assignment to olanzapine (n = 148) or risperidone (n = 120).
A Comparative Study between Olanzapine and Risperidone Regarding Drug-Induced Electrocardiographic Changes.
Cardiovasc Psychiatry Neurol
October 2014
Internal Ward, Razi Psychiatric Hospital, Tehran 18664 24336, Iran.
Introduction. Among atypical antipsychotics, none has been linked to torsade de pointes. In the present study, the electrocardiographic changes induced by olanzapine have been compared with risperidone.
View Article and Find Full Text PDFECG manifestations in acute organophosphorus poisoning.
J Indian Med Assoc
February 2012
Department of Medicine, MGM Medical College, Kisanganj 855107.
A cross-sectional study was conducted to evaluate the electrocardiographic changes in 107 patients of acute organophosphorus poisoning admitted at casuality ward of MGM Medical College, Kisanganj from June 2007 to June 2010. Electrocardiographic changes were recorded before the administration of atropine. Prolonged Q-Tc interval was the commonest ECG abnormality, found in 67 patients (62.
View Article and Find Full Text PDFImmediate cardiac arrest after neostigmine administration.
J Pak Med Assoc
June 2012
Dicle University Medical School, Department of Anesthesiology and Reanimasyon, Diyarbakir, Turkey.
Many drugs used in anaesthesia have some potential fatal consequences; for example complete heart block and Q-Tc interval prolongation. Since the parasympathetic system in children is not fully developed, electrical transmission of the heart is not stable. Neostigmine is used in order to reverse neuromuscular block but it may also lead to prolongation of Q-Tc interval.
View Article and Find Full Text PDF[Effects of different altitudes on cardiac hemodynamics and electrocardiogram of healthy male adults].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
January 2012
Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, China.
Objective: To detect the changes of cardiovascular system at different altitudes, so as to prevent and predict the susceptibility to acute mountain sickness.
Methods: The test was performed with noninvasive cardiovascular monitor and electrocardiogram in healthy male Chinese members of the 25th and 26th expeditions to the antarctic kunlun station at different altitudes (40 m, 3 650 m and 4 300 m).
Results: Compared with 40 m, from 3 650 m to 4 300 m, heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI) significantly increased (P < 0.
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