AI Article Synopsis
- Hypersecretion of albumin in urine among type 2 diabetes patients is linked to higher rates of cardiovascular disease and kidney complications.
- In a study of 65 type 2 diabetes patients, microalbuminuria was found in 37%, with men showing a significantly higher prevalence than women (53% vs. 23%).
- The study highlights that microalbuminuria is associated with uncontrolled blood glucose, higher systolic blood pressure, and increased risk of ischemic heart disease, particularly in patients aged 65 and older, suggesting the need for close monitoring and management.
Article Abstract
Prospective studies showed that hypersecretion of albumin in the urine of patients with type 2 diabetes mellitus is associated with high morbidity and mortality from cardiovascular disease and nephropathy. 65 type 2 diabetes from 6 family medicine practices were studied. Microalbuminuria was found in 37% and was significantly more common in men than in women (53% and 23%, respectively; p < 0.02). Uncontrolled blood glucose levels were also more common in men (p < 0.03). Using logistic regression with microalbuminuria as the dependent variable, a significant correlation was found with male gender, fasting blood glucose 155 mg/dl or more, and systolic blood pressure 159 mm Hg or higher. Among those with microalbuminuria, ischemic heart disease was significantly more common in those 65 years or older than in those younger (p = 0.02). This study strengthens the assumption that type 2 diabetics with microalbuminuria might be at greater risk for developing ischemic heart disease. Strict detection and control are recommended.
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