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Determining the optimal antibiotic duration for skin and soft tissue infections.
Curr Opin Infect Dis
January 2025
Department of Medicine, Clínica Rotger Quironsalud, Palma de Mallorca, Spain.
Purpose Of Review: Optimal duration of therapy in SSTIs - a heterogeneous group of infections - remains unknown. The advances in knowledge of antibiotic duration of treatment in selected SSTIs that can impact clinical practice and published in the last 18 months are reviewed.
Recent Findings: Recent evidence indicates that few patients receive guideline concordant empiric antibiotics and appropriate duration in the United States, although this likely can be extrapolated to other countries.
Linear IgA bullous dermatosis-a fifty year experience of Warsaw Center of bullous diseases.
Front Immunol
January 2025
Department of Immunodermatology, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Masovian, Poland.
Linear IgA bullous dermatosis (LABD) is a rare subepidermal blistering disorder characterized by the presence of linear IgA deposits at the basement membrane zone (BMZ) by direct immunofluorescence (DIF). This entity was first described by Chorzelski and Jablonska from Warsaw Center of Bullous Diseases, Poland. The disease affects children and adults, whereby they differ in terms of clinical picture and course.
View Article and Find Full Text PDFAutomating hock wound detection in dairy cattle.
JDS Commun
January 2025
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
Hock scoring in dairy cattle is a crucial welfare assessment tool used to evaluate the condition of a cow's hocks, particularly for signs of injury, swelling, or lesions. These scores provide insight into the overall well-being of the animals and are essential for ensuring proper management and housing conditions. Accurate hock scoring is vital because it can indicate issues such as poor bedding quality or inadequate space, which directly affect the health and productivity of the herd.
View Article and Find Full Text PDFEstablishment and validation of a nomogram for coronary artery lesions in children with Kawasaki disease.
Front Cardiovasc Med
January 2025
Clinical Laboratory, Children's Hospital Affiliated to Shandong University, Jinan, China.
Background: The nomogram is a powerful and robust tool in disease risk prediction that summarizes complex variables into a visual model that is interpretable with a quantified risk probability. In the current study, a nomogram was developed to predict the occurrence of coronary artery lesions (CALs) among patients with Kawasaki disease (KD). This is especially valuable in the early identification of the risk of CALs, which will lead to proper diagnosis and treatment to reduce their associated complications.
View Article and Find Full Text PDFA simple plan strategy to optimize the biological effective dose delivered in robotic radiosurgery of vestibular schwannomas.
Phys Med Biol
January 2025
Radiotherapy and Radiosurgery department, Iatropolis Clinic, 54 Ethnikis Antistaseos ave., Athens, Attica, 15231, GREECE.
Using the concept of biologically effective dose (BED), the effect of sublethal DNA damage repair (SLR) on the bio-efficacy of prolonged radiotherapy treatments can be quantified (BED). Such treatments, lasting more than 20 min, are typically encountered in stereotactic radiosurgery (SRS) applications using the CyberKnife (CK) and Gamma knife systems. Evaluating the plan data from 45 Vestibular Schwannoma (VS) cases treated with single fraction CK-SRS, this work demonstrates a statistically significant correlation between the marginal BEDSLR delivered to the target (m-BEDSLR) and the ratio of the mean collimator size weighted by the fraction of total beams delivered with each collimator ((_w^m)Cs), to the tumor volume (Tv).
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