The priority function of the lymphoid system is considered not only as the basis for immunological reaction but also as a system which synthesizes different substances of peptide and nucleotide nature that equally determines the specific and unspecific resistance of the body to the action of antigenic and non-antigenic factors of the environment. The lymphoid system role in fatigue, old age is stressed a leading mechanism in these processes on the basis of low-molecular lymphopeptides synthetized by this system and providing the general resistance of the body and specific function of the morphofunctional systems.

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