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Association between diabetes mellitus and tinnitus: A meta-analysis.
Biomol Biomed
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, The Affiliated Zhuzhou Hospital Xiangya Medical College CSU, Zhuzhou, China.
Diabetes mellitus (DM) has been suggested as a potential risk factor for tinnitus, but evidence remains inconclusive. This meta-analysis aimed to evaluate the association between DM and tinnitus by systematically reviewing and synthesizing data from observational studies. A comprehensive literature search was conducted in PubMed, Embase, and Web of Science up to August 16, 2024.
View Article and Find Full Text PDF18F-DCFPyL PET/MRI Radiomics for Intraprostatic Prostate Cancer Detection and Metastases Prediction Using Whole-Gland Segmentation.
Br J Radiol
January 2025
Joint Department of Medical Imaging, University Medical Imaging Toronto (UMIT), University Health Network, Mount Sinai Hospital & Women's College Hospital; University of Toronto, Toronto, ON, Canada.
Objectives: To evaluate 18F-DCFPyL-PET/MRI whole-gland-derived radiomics for detecting clinically significant (cs) prostate cancer (PCa) and predicting metastasis.
Methods: Therapy-naïve PCa patients who underwent 18F-DCFPyL PET/MRI were included. Whole-prostate-segmentation was performed.
Dynamine 3 as a Diagnostic and Prognostic Biomarker in Pancreatic Cancer: Implications for Early Detection and Targeted Therapy.
Biomarkers
January 2025
Hacettepe University, Faculty of Medicine, Deparment of Medical Oncology, Ankara, Turkey.
Background: Dynamins are defined as a group of molecules with GTPase activity that play a role in the formation of endocytic vesicles and Golgi apparatus. Among them, DNM3 has gained recognition in oncology for its tumor suppressor role. Based on this, the aim of this study is to investigate the effects of the DNM3 gene in patients diagnosed with pancreatic cancer using bioinformatics databases.
View Article and Find Full Text PDFMicroplastic accumulation in various bird species in Turkey.
Environ Toxicol Chem
January 2025
Biology Department, Faculty of Arts and Sciences, University of Recep Tayyip Erdogan, Merkez, Rize, Türkiye.
Plastic pollution constitutes one of the major environmental problems of our time, and in recent years, it has emerged as a significant threat to the environment and to various organisms, including bird species. In this context, this study, which provides the first data in Türkiye, aimed to determine the level of microplastic (MP) pollution in 12 bird species (Eurasian buzzard; short-toed snake-eagle; white stork; northern long-eared owl; common barn-owl; ruddy shelduck; Eurasian eagle-owl; scarlet macaw; common pheasant; Indian peafowl; common kestrel; and gray parrot). The results indicate that MPs were detected in 50% of the specimens (n = 20), with an average of one MP/item per individual.
View Article and Find Full Text PDFCorneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork.
Transl Vis Sci Technol
January 2025
Department of Ophthalmology, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Purpose: Regulating intraocular pressure (IOP), mainly via the trabecular meshwork (TM), is critical in developing glaucoma. Whereas current treatments aim to lower IOP, directly targeting the dysfunctional TM tissue for therapeutic intervention has proven challenging. In our study, we utilized Dexamethasone (Dex)-treated TM cells as a model to investigate how extracellular vesicles (EVs) from immortalized corneal stromal stem cells (imCSSCs) could influence ANGPTL7 and MYOC genes expression within TM cells.
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