AI Article Synopsis
- The first report using positron emission tomography (PET) shows increased metabolism in brain areas near the inflamed hippocampus during acute herpes simplex virus (HSV-1) encephalitis.
- A study focused on a 61-year-old patient revealed that neuropsychiatric symptoms recurred one month after recovering from HSV-1 encephalitis.
- A follow-up PET scan indicated decreased metabolism in the infected temporal lobe, helping to rule out a recurrence of the active infection.
Article Abstract
This first known positron emission tomography report on metabolic changes in acute herpes simplex virus (HSV-1) encephalitis demonstrates focal hypermetabolism in areas of cerebral cortex adjacent to actively inflamed hippocampus acutely infected with HSV-1. When neuropsychiatric symptoms recurred in a previously healthy 61-year-old patient 1 month after recovering from acute HSV-1 encephalitis, repeat positron emission tomography with fluorodeoxyglucose was helpful in ruling out recurrent active infection by showing marked hypometabolism throughout the previously infected temporal lobe.
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| http://dx.doi.org/10.1111/jon199442104 | DOI Listing |
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