Excessively high concentration of halothane vapor was delivered to the inspiratory gas mixture due to the vaporizer malfunction (Fluotec 4). After disassembling the vaporizer, corrosion was observed on the internal components. This was considered as the reason for the high halothane output. Proper regular check up, use of appropriate monitoring devices, and a preuse equipment checklist may help improve the quality of patient care and decrease the morbidity and mortality associated with anesthesia equipment. Anesthesia machines should receive regular check up at least once a year and anesthesia providers should routinely use an equipment checklist. It is also important to realize that anesthesiologist's senses of sight, hearing, touch, and smell are exceedingly reliable monitors for decreasing the incidence of anesthesia mishaps.
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J Anim Physiol Anim Nutr (Berl)
January 2025
Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Animal Nutrition, Braunschweig, Germany.
Bone damages in laying hens are of great concern in poultry farming. Besides various risk factors like housing systems or nutrient supply during egg production, it has often been hypothesized that genetically high-performing laying hens may be more prone to bone damages. The relevance of dietary support during the rearing period of pullets for optimal bone development has been little addressed so far.
View Article and Find Full Text PDFPLoS One
January 2025
State Key Laboratory of Automotive Safety and Energy, School of Vehicle and Mobility, Tsinghua University, Beijing, China.
This study tried to focus on the older drivers' group and explore the impact factors of injury severity involving older drivers from geo-spatial analysis. To reach the goal, a spatial analysis was proposed employing geographic information systems (GIS) with a case study application to two counties in Nevada. First, crash clusters were explored using Density-Based Spatial Clustering of Applications with Noise (DBSCAN) approach to investigate the spatial crash pattern for older drivers, and determine high risk locations of injury severity.
View Article and Find Full Text PDFPLoS One
January 2025
Institute of Natural Antioxidants and Anti-Inflammation, Dali University, Dali, Yunnan, China.
Oxidative damage, oxidative inflammation, and a range of downstream diseases represent significant threats to human health. The application of natural antioxidants and anti-inflammatory agents can help prevent and mitigate these associated diseases. In this study, we aimed to investigate the effectiveness of walnut green husk (WNGH) as an antioxidant and anti-inflammatory agent in an in vitro setting.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Electrical and Electronic Engineering, Pabna University of Science and Technology, Pabna, Bangladesh.
Waterborne bacteria pose a serious hazard to human health, hence a precise detection method is required to identify them. A photonic crystal fiber sensor that takes into account the dangers of aquatic bacteria has been suggested, and its optical characteristics in the THz range have been quantitatively assessed. The PCF sensor was designed and examined as computed in Comsol Multiphysics, a program in which uses the method of "Finite Element Method" (FEM).
View Article and Find Full Text PDFEnzymatic asymmetric synthesis of l-phenylglycine by amino acid dehydrogenases has potential for industrial applications; however, this is hindered by their low catalytic efficiency toward high-concentration substrates. We identified and characterized a novel leucine dehydrogenase (LeuDH) with a high catalytic efficiency for benzoylformic acid via directed metagenomic approaches. Further, we obtained a triple-point mutant LeuDH-EER (D332E/G333E/L334R) with improved stability and catalytic efficiency through the rational design of distal loop 13.
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