Evaluation of apical seal with Renew (calcium hydroxide) and Synthograft (tricalcium phosphate) in teeth with open apices.

The study was conducted in vivo (30 teeth) and in-vitro (135 teeth) to evaluate the leakage of apical plug with Renew, Synthograft and Control. In-vivo it was observed that Renew is significantly effective and it showed its immediate effect after filling whereas the Synthograft is not effective immediately but it is effective after 3 months and in control group the apical plug was effective after six months. When examined in vitro, it was observed that there was more leakage in Synthograft and control as compared to Renew in anterior, premolars and molars.