Intraaortic balloon counterpulsation was used to wean a 71-year-old man from cardiopulmonary bypass. Thirty-six hours after insertion, the internal lumen of the Datascope balloon fractured, releasing an unknown quantity of helium into the patient's circulation. Left-sided hemiparesis developed, secondary to a right hemispheric infarction.
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Gastrointest Endosc
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Division of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, 48202, USA.
Background And Aims: Efficacy and safety of EUS-guided placement of lumen-apposing metal stents (LAMS) has been reported yet advantage of using 15-mm LAMS over 10-mm LAMS yet to be explored.
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Department of Surgery, Oncology and Gastroenterology, University of Padua.
Among the various factors implicated in the pathogenesis of gastroesophageal reflux disease (GERD), visceral hypersensitivity and mucosal resistance have been recently re-evaluated in relation to the increasing phenomenon of proton pump inhibitor failure, particularly in patients with nonerosive reflux disease (NERD). Intensive research has allowed us to understand that noxious substances contained in the refluxate are able to interact with esophageal epithelium and to induce the elicitation of symptoms. The frequent evidence of microscopic esophagitis able to increase the permeability of the mucosa, the proximity of sensory afferent nerve fibers to the esophageal lumen favoring the higher sensitivity to noxious substances and the possible activation of inflammatory pathways interacting with sensory nerve endings are pathophysiological alterations confirming that mucosal resistance is impaired in GERD patients.
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