The purpose of this study is to investigate a relationship between the postoperative change of exercise capacity judged by the change of peal oxygen consumption and the pulmonary blood flow of the residual lung after lobectomy. Twenty eight patients undergoing lobectomy for lung cancer received an exercise tolerance test and 99mTc-MAA perfusion lung scans before and after lobectomy. The change rate in the peak level of oxygen consumption (peak VO2) did not differ depending on the number of resected sub-segments. A good correlation was found between the reduction of perfusion ratio of the lung of the operated side (delta Q) and that of the peak level of oxygen consumption (delta peak VO2) (r = 0.74, p < 0.01). A reduction in delta Q and delta peak VO2 was remarkable in patients with postoperative respiratory complications such as atelectasis and pulmonary air leakage. These results indicate that the perfusion lung scans at rest before and after surgery would be able to predict the change of exercise capacity after lobectomy.
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