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Microbiome metabolic capacity is buffered against phylotype losses by functional redundancy.
Appl Environ Microbiol
January 2025
Department of Microbiology, Ohio State University, Columbus, Ohio, USA.
Unlabelled: Many animals contain a species-rich and diverse gut microbiota that likely contributes to several host-supportive services that include diet processing and nutrient provisioning. Loss of microbiome taxa and their associated metabolic functions as result of perturbations may result in loss of microbiome-level services and reduction of metabolic capacity. If metabolic functions are shared by multiple taxa (i.
View Article and Find Full Text PDFSpatiotemporal variation in size-dependent growth rates in small isolated populations of Arctic charr ().
R Soc Open Sci
January 2025
School of Biology, University of St Andrews, St Andrews, UK.
As a key life-history trait, growth rates are often used to measure individual performance and to inform parameters in demographic models. Furthermore, intraspecific trait variation generates diversity in nature. Therefore, partitioning out and understanding drivers of spatiotemporal variation in growth rate is of fundamental interest in ecology and evolution.
View Article and Find Full Text PDFAdherence to community-based lung cancer screening in the Yorkshire Lung Screening Trial.
Lung Cancer
January 2025
Department of Respiratory Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Health Sciences, University of Leeds, Leeds, UK. Electronic address:
Introduction: Lung cancer screening saves lives by detecting cancers early, but continued adherence to screening rounds is required for participants to experience the maximum clinical benefit. Here we describe factors associated with screening adherence in the Yorkshire Lung Screening Trial.
Methods: All eligible individuals following baseline (prevalent) screening were invited for a biennial incident screen in a community setting.
Characterization of the host specificity of the SH3 cell wall binding domain of the staphylococcal phage 88 endolysin.
Arch Microbiol
January 2025
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor, 43400, Malaysia.
Bacteriophages produce endolysins at the end of the lytic cycle, which are crucial for lysing the host cells and releasing virion progeny. This lytic feature allows endolysins to act as effective antimicrobial alternatives when applied exogenously. Staphylococcal endolysins typically possess a modular structure with one or two enzymatically active N-terminal domains (EADs) and a C-terminal cell wall binding domain (CBD).
View Article and Find Full Text PDFPhotobioreactor design utilizing procedural three-dimensional modelling and ray tracing.
J R Soc Interface
January 2025
Faculty of Information Technology, University of Jyväskylä, Jyvaskyla, Finland.
The design of photobioreactors for microalgae cultivation aims to achieve an architecture that allows the most efficient photosynthetic growth. The availability of light at wavelengths that are important for photosynthesis is therefore particularly crucial for reactor design. While testing different reactor types in practice is expensive, simulations could effectively limit the range of material and reactor design options.
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