The action of the drug on the electrocardiograph and clinical investigations were carried out on 55 patients treated with Fludilat. It was shown that in vagotonic subjects and patients with subendocardial ischemia the high T wave in the ECG becomes flattened, in some of the cases the QT interval is prolonged and the U wave larger, parallel with the improvement in the symptoms. A better clinical effect than previously was observed as as result of the antianginal action of Fludilat.
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Zh Nevrol Psikhiatr Im S S Korsakova
November 2015
Aim: To perform a differential analysis of the efficacy of combination therapy by the drugs with different modalities (mexidol, aescusan, halidorum) in outpatients with chronic cerebral ischemia (CCI), stages I- III.
Material And Methods: A study included 50 patients with CCI of atherosclerotic, hypertensive and mixed genesis (stage I - 20 patients, stage II - 20, stage III - 10 patients). In addition to somatic therapy, patients received three courses of mexidol, halidorum and aescusan combination therapy during 6 weeks with a 3 month interval between the courses.
Clin Toxicol (Phila)
November 2014
Ontario and Manitoba Poison Centre, Toronto, ON , Canada.
Context: Calcium channel blocker poisoning is a common and sometimes life-threatening ingestion.
Objective: To evaluate the reported effects of treatments for calcium channel blocker poisoning. The primary outcomes of interest were mortality and hemodynamic parameters.
Auris Nasus Larynx
February 2014
Department of Nuclear Medicine, Mustafa Kemal University Medical Faculty, Hatay, Turkey.
Objective: The aim of this study is to discuss the use of non-vascularized bone grafts in mandibular reconstruction and their viability.
Methods: In this study, 11 patients with mandibular defect treated by surgery using non-vascularized bone grafts between 2011 and 2012 were reviewed. All patients underwent preoperative and postoperative 3-dimensional computerized tomography scan for surgical planning and evaluation of success after surgery.
Zh Nevrol Psikhiatr Im S S Korsakova
April 2009
An aim of the study was to assess efficacy and safety of an injection form of galidor (bencyclan) in patients with chronic cerebral vascular diseases in cases of emergency. Sixty patients with discirculatory encephalopathy (DE), including 38 with basilar insufficiency, were treated. Mean age of patients was 59,7 years.
View Article and Find Full Text PDFEksp Klin Farmakol
February 2009
Patients with a chronic brain ischemia of stages I-II on the background of hypertension and/or cerebral atherosclerosis are characterized by energy insufficiency of the metabolism, as estimated by the activity of succinate dehydrogenase in peripheral blood lymphocytes. Within the framework of randomized comparative investigation of the efficiency of actovegin and mexidol in the complex therapy of a chronic brain ischemia, positive dynamics in reduction of the clinical semiology, restoration of cognitive processes in the brain, and reduction of the expression of subjective manifestations of the disease is established. On this background, the administration of mexidol led to restoration of the energy exchange due to substrate effects of the Krebs cycle intermediates present in its structure.
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