The human homologue of the retroviral oncogene qin maps to chromosome 14q13.

Proc Natl Acad Sci U S A

Jefferson Cancer Institute, Jefferson Medical College, Philadelphia, PA 19107.

Published: April 1994

Chromosomal mapping of the human QIN gene (renamed FKH2 by the Human Genome Organization Nomenclature Committee) was initially accomplished by correlation of the presence of the QIN locus with specific chromosome regions in a rodent-human hybrid panel. This analysis revealed that the human QIN gene maps to chromosome region 14q11.2-->14q32, between the TCR and IGH loci. Further analysis by fluorescence in situ hybridization techniques with a human QIN genomic clone refined the human QIN gene localization to 14q13.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC43631PMC
http://dx.doi.org/10.1073/pnas.91.9.3616DOI Listing

Publication Analysis

Top Keywords

human qin
16
qin gene
12
maps chromosome
8
human
6
qin
6
human homologue
4
homologue retroviral
4
retroviral oncogene
4
oncogene qin
4
qin maps
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!