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SPHINX, a Guardian of Wisdom.
Gut
December 2024
Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
Difficult cannulation during endoscopic retrograde cholangiopancreatography-needle-knife precut versus transpancreatic sphincterotomy on the basis of successful cannulation and adverse events.
Surg Endosc
December 2024
Department of Research and Development and Department of Surgery, Central Hospital, Region Kronoberg, Strandvägen 8, 351 85, Växjö, Sweden.
Article Synopsis
- This study compared two alternative techniques, transpancreatic sphincterotomy (TPS) and precut sphincterotomy (PCS), for accessing the biliary tree during difficult ERCP procedures.
- TPS showed higher successful cannulation rates (86.5%) compared to PCS (69.7%), but both were lower than the standard sphincterotomy control group (92.4%).
- Despite higher cannulation success, TPS was associated with more adverse events (24.1%) compared to PCS (18.8%) and the control group (15.5%), with increased rates of pancreatitis and perforation in the TPS group.
Biliary sepsis, characterized by contamination and infection of the biliary tract, poses a serious medical issue with detrimental effects on the patients. While cholecystectomy is the usual treatment for symptomatic gallstones, the most desirable management approach for biliary sepsis remains debated, prompting a scientific evaluation of the long-term effects of cholecystectomy. To compare the long-term outcomes of biliary sepsis in patients undergoing cholecystectomy versus conservative management (CM), this study will systematically review the existing literature to clarify differences in recurrence rates, complication rates, and overall survival.
View Article and Find Full Text PDFComparative efficacy and safety of three endoscopic techniques for the treatment of large common bile duct stones (≥ 15 mm): Long-term follow-up.
Gastrointest Endosc
December 2024
Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China. Electronic address:
Background & Aims: The effectiveness of endoscopic papillary large balloon dilation (EPLBD) alone versus EPLBD combined with endoscopic sphincterotomy (EST) in treating large common bile duct stones (CBDS, ≥ 15 mm) remains unclear. This study aimed to evaluate the safety and treatment outcomes of EPLBD combined with limited or large EST versus EPLBD alone in removing large CBDS.
Methods: Between January 2013 and September 2024, 408 patients underwent EPLBD, either alone or in combination with EST, to treat large CBDS (≥ 15 mm).
Efficacy and safety of fully covered self-expanding metal stents in the management of Post sphincterotomy bleeding: a Systematic Review and Meta-analysis.
Gastrointest Endosc
December 2024
Division of Gastroenterology, Thomas Jefferson University Hospital, Philadelphia, PA. Electronic address:
Background And Aims: Fully covered self-expandable metallic stents (FCSEMS) are often used in the management of post-sphincterotomy bleeding which is refractory to conventional endoscopic treatments. In this meta-analysis, we have evaluated the efficacy and safety of FCSEMS in the management of post-sphincterotomy bleeding.
Methods: We reviewed several databases from inception to November 6, 2024 to identify studies that evaluated the efficacy, and/or safety of FCSEMS in the management of post sphincterotomy bleeding.
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