Antisera obtained for certain hormones possessed a high specific effect on homologous hormones. Radioimmunological methods were worked out for determination of these hormones in the blood serum of humans and animals. Clinical use of the above antisera for determination of dehydroepiandrosterone and androstenedione in humans revealed than it could be useful to determine dehydroepiandrosterone in some forms of hypogonadism. Androstenedione is often increased in female hirsutism.
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