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Catecholamines excretion has been analyzed in 36 patients suffering from parkinsonism and in 30 normal subjects. Curable patients demonstrated the same proportion of epinephrine and norepinephrine/DOPA excretion as normal subjects did. In resistant to treatment subjects and in unlikely curable the above coefficients were significantly larger. It is suggested that enhanced activity of peripheral sympathoadrenal system may serve a factor of low response to medication.

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