According to a proposal of the International Society for the Study of Hypertension in Pregnancy (ISSHP) the definition of hypertension is based on a diastolic blood pressure of 90 mmHg or more. Systolic and mean arterial blood pressure (e.g. MAP II) are not be taken into account. Out of a clear defined district the totality of n = 2259 pregnant women has been strictly supervised till to delivery and afterwards. The frequency of hypertension according to the old ACOG-definition was calculated to be 15.9% (n = 360). According to the newer ISSHP-definition it was 12.7% (n = 287). To detect severe and hazardous cases the newer ISSHP-definition seems to be better than the older definition of ACOG. Therefore, the acceptance of the ISSHP-proposal is recommended.
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JAMA Netw Open
January 2025
Magee-Womens Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, Epidemiology and Clinical and Translational Research, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: Chronic hypertension and preeclampsia are leading risk enhancers for maternal-neonatal morbidity and mortality. Severe maternal morbidity (SMM) indicators include heart, kidney, and liver disease, but studies have not excluded patients with preexisting diseases that define SMM. Thus, SMM risks for uncomplicated chronic hypertension specific to preeclampsia remain unclear.
View Article and Find Full Text PDFArch Gynecol Obstet
January 2025
Department of Obstetrics and Gynecology, Division of Perinatology, Ankara Etlik City Hospital, Ankara, Turkey.
Introduction: Pregnancy induces a hypercoagulable state, characterized by increased coagulation factors and decreased anticoagulants, alongside ongoing fibrinolysis marked by elevated D-dimer (DD) levels. Reference values for DD in pregnancy often exceed the non-pregnant cutoff due to these changes. Elevated DD levels are common in late pregnancy and may correlate with complications such as gestational diabetes, hypertension, and preterm delivery, particularly in cases of preterm premature rupture of membranes (PPROM).
View Article and Find Full Text PDFCureus
December 2024
Coordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
Background: Allostatic load and oxidative stress (OS) markers differ in women with and without preeclampsia. However, there is no difference in allostatic load and OS markers between late-onset preeclampsia (L-OP) and early-onset preeclampsia (E-OP). This study aimed to compare the concentrations of allostatic load and OS markers in pregnant women with L-OP and E-OP.
View Article and Find Full Text PDFPediatr Diabetes
January 2025
Division of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Objective: We sought to evaluate the risk of preterm labor and hypertensive disorders in adolescent pregnancies with and without diabetes.
Methods: We evaluated 1,843,139 adolescents (≤20 years old) with labor and delivery admissions in the national Kids' Inpatient Database (KID) in years 2006, 2009, 2012, 2016, and 2019. International classification of disease codes was used to identify diabetes and medical factors affecting pregnancy.
Am J Case Rep
January 2025
Department of Neonatology, The First Division Hospital of Xinjiang Production and Construction Corps, Akesu, Xinjiang, China.
BACKGROUND Ureaplasma urealyticum (UU) is a common microorganism that has been associated with a variety of obstetric and neonatal complications, such as infertility, stillbirth, histologic chorioamnionitis, neonatal sepsis, respiratory infections, and central nervous system infections. However, it is rare for it to cause severe neonatal asphyxia. This rarity is the focus of our case report, which aims to highlight the potential severity of UU infections in newborns.
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