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Study on the effect of Western medicine caltrate D combined with traditional Chinese medicine eight section brocade practice therapy on preventing postmenopausal osteoporosis.
Pak J Pharm Sci
March 2025
Orthopedics Department of Beijing Xiaotangshan Hospital, Xiaotangshan Town, Changping District, Beijing, China.
Caltrate D is a commonly used drug in the treatment of postmenopausal osteoporosis (PMOP), but the effect of single application is not ideal. Therefore, to investigate the eight section brocade therapy combined with caltrate D effect in preventing and treating PMOP. From January 2021 to June 2022, 110 postmenopausal women with decreased bone mass were selected and randomized into group A (n = 54) and group B (n = 56).
View Article and Find Full Text PDFAdapting the MUSIQ Calculator for Practice Facilitators to Evaluate Primary Care Clinic Performance in a Colorectal Cancer Screening Quality Improvement Project.
J Prim Care Community Health
March 2025
West Virginia University School of Medicine, Morgantown, WV, USA.
The Model for Understanding Success in Quality (MUSIQ) is a framework designed to understand the contextual factors that can influence healthcare quality improvement (QI) initiative implementation. The MUSIQ calculator was originally developed to help clinics identify contextual factors that may affect QI success. This retrospective study adapted the MUSIQ calculator to serve as an evaluative tool for practice facilitators engaged in a colorectal cancer screening initiative.
View Article and Find Full Text PDFAssociation between volume of processed plasma and total bilirubin reduction during plasma adsorption for severe liver disease.
Eur J Med Res
March 2025
Center of Infectious Diseases, West China Hospital of Sichuan University, No.37 GuoXue Xiang, Wuhou District, Chengdu, 610041, China.
Background: The double plasma molecular adsorption system (DPMAS) is a crucial therapeutic modality for the management of severe liver disease. Current literature reports considerable variability in the volume of processed plasma (VPP) utilized during DPMAS treatment, and there is currently no consensus on the appropriate VPP. We aimed to investigate the relationship between VPP and changes in total bilirubin levels during DPMAS treatment.
View Article and Find Full Text PDFPathologic response rates in HER2-low versus HER2-zero early breast cancer patients receiving neoadjuvant therapy: a systematic review and meta-analysis.
Breast Cancer Res
March 2025
Federal University of Pará, R. Augusto Corrêa, Guamá, nº01, Belem, PA, 66075-110, Brazil.
Background: Currently, the primary methods for detecting HER2 expression levels are immunohistochemistry (IHC) and in situ hybridization (ISH), with the traditional standard being a HER2-positive score of 3 + accompanied by ERBB2 gene amplification detected through ISH. However, a new entity has recently emerged: HER2-low, defined as HER2 IHC 1 + or 2 + with negative ISH. HER2-low breast cancer, representing 45-60% of all HER2-negative tumors, has distinct biological characteristics and uncertain responses to conventional HER2-targeted therapies.
View Article and Find Full Text PDFF-box protein FBXO21 overexpression inhibits the proliferation and metastasis of clear cell renal cell carcinoma and is closely related to the CREB pathway and tumor immune cell infiltration.
J Transl Med
March 2025
Department of Urology, the First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, Zhejiang, People's Republic of China.
Background: Many studies have shown that F-box proteins regulate epithelial-mesenchymal transition, which is closely related to tumor metastasis. However, there is still limited research on the role of F-box proteins in renal cell carcinoma (RCC).
Methods: Public databases were used to screen differentially expressed genes among 37 F-box proteins in clear cell RCC (ccRCC).
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