Radiologically osteofibrous dysplasia of the tibia is characterized by an eccentrically localized osteolytic lesion in the diaphysis with the appearance of ground glass. However, this is a very rare lesion, making a correct diagnosis difficult, especially since fibrous dysplasia and adamantinoma of the tibia have to be taken into account in the differential diagnosis of the disease. A definitive diagnosis can only be made histologically. The rather aggressive growth pattern of osteofibrous dysplasia as compared to fibrous dysplasia that has been reported in literature should not be generalized and it must be taken into consideration that surgery may be performed too early during the growth phase.
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