Macrophage response to experimental implantation of polypropylene prostheses.

Eur Surg Res

Department of Morphological Sciences and Surgery, Faculty of Medicine, University of Alcala de Henares, Madrid, Spain.

Published: April 1994

We have assessed the macrophage response to polypropylene mesh (Marlex) implanted into the abdominal wall of New Zealand white rabbits, using RAM-11, a monoclonal antibody specific for rabbit macrophages. The response diminishes during the course of the first 90 days after implantation, although the presence of other cell types typical of foreign-body reactions increases. We have also confirmed the high degree of integration of the biomaterial into the wall achieved after 9 weeks. This has been determined using light and scanning electron microscopy. Likewise, we have observed the formation of numerous adhesions between the polypropylene mesh and the viscera of the abdominal cavity.

Download full-text PDF

Source
http://dx.doi.org/10.1159/000129317DOI Listing

Publication Analysis

Top Keywords

macrophage response
8
polypropylene mesh
8
response experimental
4
experimental implantation
4
implantation polypropylene
4
polypropylene prostheses
4
prostheses assessed
4
assessed macrophage
4
response polypropylene
4
mesh marlex
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!