The activities of CuZn-SOD and Mn-SOD in rat plasma and liver dropped (P < 0.05 and P < 0.01, respectively) but LPO levels increased significantly (P < 0.01) after the rats were got into plateau from plain rapidly. The decrease of the activities of SODs was associated with the rise of LPO levels. The results suggested that the formation of free radicals in the body increased and the antioxidant ability lowered after their rapid entry into plateau from plain, and it was unfavourable to their acclimatization to plateau.
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