Patients often have hypertension after successful kidney transplantation. In the long term, this hypertension adds to patient mortality and morbidity. The widespread use of cyclosporine appears to have changed the nature of posttransplantation hypertension. In humans, cyclosporine-associated hypertension seems to involve sodium retention and stimulation of the sympathetic nervous system.
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http://dx.doi.org/10.1016/s0272-6386(12)81015-8 | DOI Listing |
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