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VP4 genotyping of human rotavirus in the United States. | LitMetric

VP4 genotyping of human rotavirus in the United States.

J Clin Microbiol

Division of Molecular Biological Research and Evaluation, Food and Drug Administration, Washington, DC 20204.

Published: January 1994

The VP4 (P) and VP7 (G) types of 171 rotavirus isolates obtained from children with diarrhea in the United States were characterized by PCR typing assays. Strains P1G1 predominated (71%); this was followed by strains P1G3 (20%) and P2G2 and P1G4 (2% each). Mixed types were identified in five (3%) specimens. Two (1%) strains bearing the P3 genotype (P3G1 and P3G2) were found in children with severe dehydrating diarrhea, although the P3 genotype has been regarded as a possible marker for virus attenuation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC262997PMC
http://dx.doi.org/10.1128/jcm.32.1.205-208.1994DOI Listing

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