AI Article Synopsis

  • M. ulcerans strongly adheres to human tissue, causing necrosis, whereas M. tuberculosis also grows but not as effectively.
  • M. xenopi shows minimal growth on human tissue surfaces compared to the other two bacteria.
  • The differences in how these bacteria interact with human tissue are examined in the context of understanding Buruli ulcer's development.

Article Abstract

M. ulcerans grows in close association with the surface of cultured human foetal and adult tissue and produces necrosis. M. tuberculosis grows also but M. xenopi grows little or not at all. The two first named seem to stick well to the tissue surface and the last does not. These results are discussed in relationship to the pathogenesis of Buruli ulcer.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072745PMC

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