The application of output value analysis, a type of benefit/cost analysis, to a psychiatric patient population is reported. A method for discounting the value of the program if a patient was readmitted within a year after discharge was introduced. The application of this discount factor reduces the value produced by the program and thereby reduces both productivity and effectiveness indices. When applied to groups known to differ in readmission rates, such as first admissions and readmissions or voluntary and involuntary admissions, the discount factor can accentuate group differences markedly. When selected diagnostic groups were compared, the discount factor could even reverse the relative standing of the groups.
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http://dx.doi.org/10.1007/BF00880773 | DOI Listing |
PLoS One
January 2025
Division of Global HIV & TB, US Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Background: In Uganda, adolescent girls', and young women's (AGYW-15-24 years) current HIV prevalence is fourfold compared with their male counterparts due to compounded social, economic, and environmental factors. Using the Protective Motivation Theory (PMT), we explored HIV-acquisition risk sources and perceived protective factors from AGYW and caregivers' perspective.
Materials And Methods: During 2018, we conducted a qualitative study guided by PMT to explore factors influencing HIV acquisition among AGYW.
Entropy (Basel)
January 2025
School of Software Engineering, Xi'an Jiaotong University, Xi'an 710049, China.
Non-stationary multi-armed bandit (MAB) problems have recently attracted extensive attention. We focus on the abruptly changing scenario where reward distributions remain constant for a certain period and change at unknown time steps. Although Thompson sampling (TS) has shown success in non-stationary settings, there is currently no regret bound analysis for TS with uninformative priors.
View Article and Find Full Text PDFPharmacoecon Open
January 2025
HTA & Pharmaceutical Economics Department, Italian Medicines Agency (AIFA), Rome, Italy.
Background: The authorization of new therapeutic indications for drugs already reimbursed by the Italian National Health Service (NHS) represents a matter of importance. This study aims to estimate the additional discount attributed to the extension of indications (EoIs) to explore the potential correlation between spending and negotiated discounts and to find specific factors (determinants) that impact on discount.
Methods: The study focused on drugs approved in Italy between 2003 and 2017 with at least four therapeutic indications, including the first approved and EoIs, with follow-up extended until 2021 to acquire all the information on the negotiation process that has been completed.
Heliyon
January 2025
James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.
In the efforts to decarbonise the heat sector, heat pumps can offer a cost-effective transition away from fossil fuels. Water Source Heat Pumps (WSHP) can be utilised in cases where ambient water sources (river, ground water, abandoned mines water) are present. However, the economic benefits of different levels of heat pump centralisation as well as their comparative advantages over other decentralised options such as individual Air Source Heat Pumps (ASHP) or Gas Boilers (GB) remain uncertain and further investigations are necessary to fully assess their potential.
View Article and Find Full Text PDFJ Sci Med Sport
January 2025
Department of Mathematics & Statistics, University of Otago, New Zealand.
Objectives: Knee braces were introduced to sports 30 years ago. However, knee brace use for non-contact anterior cruciate ligament injury prevention intervention remains contentious due to concerns about performance hindrances. Since knee brace use is a potential modifiable risk factor, we aimed to investigate the effect of discounting and continued functional knee brace (FKB) on lower extremity power-vertical jump (VJ), acceleration, speed, and agility performance.
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