The mitotic activity of alveolar macrophages-monocytes (AM-M) from bronchoalveolar lavages of 18 male (Balb x Black 6) mice F1 has been studied twice a day: at 8.00 a. m. (9 mice) and 8.00 p. m. (9 mice). Significant diurnal variations of AM-M proliferation were found. The mitotic index was 3.07 +/- 0.3/1000 in the morning and 1.39 +/- 0.3/1000 in the evening (p < 0.002).
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