Visceral involvement, particularly of the gastrointestinal tract is common in patients with AIDS-related Kaposi's Sarcoma. A patient with AIDS and digestive Kaposi's Sarcoma who had lesions located in the mouth, pharynx and esophagus with a well-defined delimination to the esophago-gastric junction was studied A discussion and a review of the medical literature was made in order to find a physiopathological mechanism to explain this topographical selectivity.

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