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Background: Hypothyroidism is a common sequela after radiotherapy for nasopharyngeal carcinoma (NPC). Magnetic resonance imaging (MRI) has gained prominence in thyroid imaging, leveraging its non-ionizing radiation, high spatial resolution, multiparameter and multidirectional imaging. Few previous studies have investigated the evaluation of radiation-induced thyroid injury by MRI.
View Article and Find Full Text PDFEnhancing diagnostic accuracy in breast cancer: integrating novel machine learning approaches with enhanced image preprocessing for improved mammography analysis.
Pol J Radiol
December 2024
Nuclear Fuel Research School, Nuclear Science and Technology Research Institute, Tehran, Iran.
Purpose: This study explored the use of computer-aided diagnosis (CAD) systems to enhance mammography image quality and identify potentially suspicious areas, because mammography is the primary method for breast cancer screening. The primary aim was to find the best combination of preprocessing algorithms to enable more precise classification and interpretation of mammography images because the selected preprocessing algorithms significantly impact the effectiveness of later classification and segmentation processes.
Material And Methods: The study utilised the mini-MIAS database of mammography images and examined the impact of applying various preprocessing method combinations to differentiate between malignant and benign breast lesions.
Mechanically regulated microcarriers with stem cell loading for skin photoaging therapy.
Bioact Mater
April 2025
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, 325035, China.
Long-term exposure to ultraviolet radiation compromises skin structural integrity and results in disruption of normal physiological functions. Stem cells have gained attention in anti-photoaging, while controlling the tissue mechanical microenvironment of cell delivery sites is crucial for regulating cell fate and achieving optimal therapeutic performances. Here, we introduce a mechanically regulated human recombinant collagen (RHC) microcarrier generated through microfluidics, which is capable of modulating stem cell differentiation to treat photoaged skin.
View Article and Find Full Text PDFInsight into the Enhanced Removal of U(VI) with Fe-Ni Bimetallic Particles Loaded on Biochar.
Langmuir
January 2025
Institute of Plasma Physics, Hefei Institutes of Physical Science, Chinese Academy of Sciences, P.O. Box 1126, Hefei 230031, PR China.
This work develops Fe-Ni particles loaded on biochar (Fe-Ni/BC) to remove U(VI) efficiently. Fe-Ni bimetallic particles loaded on biochar (BC) can improve stability and reactivity, and the mesoporous structure of BC can effectively reduce Fe aggregation. The removal ability of Fe-Ni/BC is higher than that of Fe-Ni, BC, and Fe/BC.
View Article and Find Full Text PDFSynthesis, Structure, and Redox Reactivity of Ni Complexes Bearing a Redox and Acid-Base Non-innocent Ligand with Ni, Ni, and Ni Formal Oxidation States.
J Am Chem Soc
January 2025
Department of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea.
A series of Ni complexes bearing a redox and acid-base noninnocent tetraamido macrocyclic ligand, H-(TAML-4) {H-(TAML-4) = 15,15-dimethyl-5,8,13,17-tetrahydro-5,8,13,17-tetraaza-dibenzo[]cyclotridecene-6,7,14,16-tetraone}, with formal oxidation states of Ni, Ni, and Ni were synthesized and characterized structurally and spectroscopically. The X-ray crystallographic analysis of the Ni complexes revealed a square planar geometry, and the [Ni(TAML-4)] complex with the formal oxidation state of Ni was characterized to be [Ni(TAML-4)] with the oxidation state of the Ni ion and the one-electron oxidized TAML-4 ligand, TAML-4. The Ni oxidation state and the TAML-4 radical cation ligand, TAML-4, were supported by X-ray absorption spectroscopy and density functional theory calculations.
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