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The relationship between selected sexually transmitted pathogens, HPV and HIV infection status in women presenting with gynaecological symptoms in Maputo City, Mozambique.
PLoS One
September 2024
Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Article Synopsis
- The study examined the prevalence of sexually transmitted infections (STIs) among 233 non-pregnant women in Maputo, Mozambique, finding a high overall STI prevalence of 89%, with 63% testing positive for HPV and 24% for HIV.* -
- The majority of women reported vaginal discharge (90%), a common symptom, and 56% had co-infections with any STI and HPV, with 45% of these co-infections identified as high-risk HPV genotypes.* -
- The research utilized advanced diagnostic methods, including multiplex STD and HPV Direct Flow Chip Kits and rapid HIV tests, indicating a significant health concern in the region regarding STIs and their effective detection.*
Prevalence of sexually transmitted infections and associated risk factors among female sex workers in Guinea-Bissau.
Sex Transm Infect
October 2024
The Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Article Synopsis
- * Researchers recruited 467 women between October 2014 and May 2019, finding a striking 46.7% prevalence rate of curable STIs, with asymptomatic cases being significant, and a high ciprofloxacin resistance rate of 84%.
- * Key risk factors for STIs included age and HIV-1 infection, while using female condoms appeared protective; the findings suggest a critical need for improved STI testing and treatment efforts among this population to curb transmission.
Prevalence of sexually transmitted infections (STIs), associations with sociodemographic and behavioural factors, and assessment of the syndromic management of vaginal discharge in women with urogenital complaints in Mozambique.
Front Reprod Health
April 2024
School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Article Synopsis
- In Mozambique, a study identified a significant prevalence of non-viral STIs and HIV-1/2 among women with urogenital issues, focusing on diagnostic accuracy and sociodemographic factors.
- The research, conducted with 924 women, revealed infection rates of chlamydia (15.5%), trichomoniasis (12.1%), gonorrhoea (4.0%), and HIV-1/2 (22.3%), primarily through PCR testing.
- Findings indicated that the current syndromic management approach missed nearly 20% of infections and led to overtreatment in about 70% of cases, highlighting the need for improved STI diagnosis and treatment strategies.
Sexually transmitted infections in pregnancy and adverse pregnancy outcomes: A retrospective cohort study.
Int J Gynaecol Obstet
July 2024
Center for the AIDS Program of Research in South Africa (CAPRISA), Durban, South Africa.
Article Synopsis
- There is a high rate of asymptomatic sexually transmitted infections (STIs) among pregnant adolescent girls and young women in Africa, which is linked to pregnancy outcomes in HIV-affected regions.
- The study involved HIV-negative pregnant women in South Africa, who were tested for various STIs at the beginning and later stages of their pregnancy, with a focus on how these infections might affect their outcomes.
- Results showed that certain STIs like Mycoplasma genitalium and Trichomonas vaginalis were significantly associated with low birth weight and preterm births, suggesting a need for further research on STI testing and treatment during pregnancy.
High incidence of asymptomatic genital tract infections in pregnancy in adolescent girls and young women: need for repeat aetiological screening.
Sex Transm Infect
November 2023
Centre for the AIDS Program of Research in South Africa, CAPRISA, Durban, KwaZulu-Natal, South Africa.
Article Synopsis
- The study examines the prevalence and incidence of sexually transmitted infections (STIs) in pregnant adolescents (15-19 years) compared to older pregnant women (20-24 and >25 years) in Umlazi, South Africa.
- Findings show that pregnant adolescents have a baseline STI prevalence of 26.7%, which is not significantly lower than the 34.7% and 33.8% seen in the older age groups.
- The study highlights poor performance of syndromic management for STIs, with a low positive predictive value and many women remaining asymptomatic despite having STIs.
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