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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Background: The risk of cognitive decline in cancer survivors may be increased by platinum-based chemotherapy. Evidence indicates that physical exercise has a potential to reduce chemotherapy-related toxicity. The aim of this study was to assess effects of a 6-month aerobic-strength training on cognitive functions, metabolic flexibility, anthropometric parameters and physical fitness in testicular germ cell tumor (TGCT) survivors, treated with platinum-based chemotherapy.
View Article and Find Full Text PDFDementia Care Practice.
Alzheimers Dement
December 2024
Noesis Cognitive Center & Tech Solutions Ltd, Nicosia, Cyprus.
Background: An 84-year-old male, with 16 years of education (retired physics teacher) was admitted to a long-term rehabilitation centre to receive daily care, with cognitive decline symptoms. This study presents the data from a three-month cognitive enhancement program.
Methods: In September 2023, the patient underwent the Mini Mental State Examination (MMSE) in Greek, followed by cognitive enhancement sessions (45 minutes, twice a week) for three months.
Association of LDL-C/HDL-C Ratio With Hyperuricemia: A National Cohort Study.
Clin Transl Sci
January 2025
Department of Geriatrics, Panzhihua Central Hospital, Panzhihua, China.
Hyperuricemia (HUA) is a metabolic abnormality syndrome caused by disorders of purine metabolism. This study aimed to investigate the predictive value of the low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (LHR) for the risk of developing HUA. We extracted data from the China Health and Retirement Longitudinal Study (CHARLS) database from 2011 to 2016.
View Article and Find Full Text PDFSplit Membrane: A New Model to Accelerate All-Atom MD Simulation of Phospholipid Bilayers.
J Chem Inf Model
January 2025
CEITEC─Central European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic.
All-atom molecular dynamics simulations are powerful tools for studying cell membranes and their interactions with proteins and other molecules. However, these processes occur on time scales determined by the diffusion rate of phospholipids, which are challenging to achieve in all-atom models. Here, we present a new all-atom model that accelerates lipid diffusion by splitting phospholipid molecules into head and tail groups.
View Article and Find Full Text PDFInfluence of Persistently Elevated LDL Values on Carotid Intima Media Thickness in Elite Athletes.
High Blood Press Cardiovasc Prev
January 2025
Institute of Sport Medicine and Science, National Italian Olympic Committee, Largo Piero Gabrielli, 1, 00197, Rome, Italy.
Introduction: Carotid IMT is a recognized marker for early atherosclerotic changes and a predictor of future CV events. Previous studies showed 11% increased risk of myocardial infarction with each 0.1 mm incremental increase of carotid IMT.
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