The poly (A) tracts of RNA's from viral particles and from replicative complex belong to two classes of 180 and of 60 nucleotides in length. Those of the mRNA are homogenous and around 280 nucleotides in length. The results presented here strongly suggest the possibility of a copying mechanism in the first case and of a posttranscriptional addition in the latter.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Comprehensive Analysis of the Fourteen Complete Genome Sequences of Isolated from Species.
J Microbiol Biotechnol
December 2024
Department of Life science, Chung-Ang University, Seoul 06974, Republic of Korea.
Endosymbionts are important for insect species as they provide essential substances to the host. Due to the technical advance of NGS technology and assemblers, many endosymbionts bacterial genomes are available now. Here, we analysed fourteen endosymbiont bacterial genomes of genius, one of notorious pest species.
View Article and Find Full Text PDFBAC-browser: the tool for synthetic biology.
BMC Bioinformatics
January 2025
Research Institute for Systems Biology and Medicine, Moscow, Russian Federation.
Background: Currently, synthetic genomics is a rapidly developing field. Its main tasks, such as the design of synthetic sequences and the assembly of DNA sequences from synthetic oligonucleotides, require specialized software. In this article, we present a program with a graphical interface that allows non-bioinformatics to perform the tasks needed in synthetic genomics.
View Article and Find Full Text PDFNovel relatives of Mecsek Mountains mammarenavirus (family Arenaviridae) in hedgehogs living in different sampling areas in Hungary.
Sci Rep
January 2025
Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti út 12, Pécs, 7624, Hungary.
Mammarenaviruses (genus Mammarenavirus, family Arenaviridae) are rodent-borne zoonotic viruses consisting of 52 viral species, including ten that are pathogenic to humans. Currently, only two endemic mammarenavirus species are known in Europe: the human pathogenic Mammarenavirus choriomeningitidis (LCMV) and the recently discovered hedgehog-origin Mammarenavirus mecsekense (MEMV). In this study, 59 faecal specimens from Northern white-breasted hedgehogs (Erinaceus roumanicus) from different geographic regions in Hungary were investigated for mammarenavirus presence and complete genome characterization using newly designed screening primers by RT-semi-nested PCR and sequencing methods.
View Article and Find Full Text PDFEvaluating genome-wide and targeted forensic sequencing approaches to kinship determination.
Forensic Sci Int Genet
January 2025
Department of Genetics, Genomics & Cancer Sciences, University of Leicester, University Road, Leicester, UK. Electronic address:
Kinship determination is a valuable tool in forensic genetics, with applications including familial searching, disaster victim identification, and investigative genetic genealogy. Conventional typing of small numbers of autosomal short tandem repeats (STRs) confidently identifies only first-degree relatives. Massively parallel sequencing (MPS) can access more STRs and resolve alleles identical by length but differing in sequence (isoalleles), which may increase the power of kinship estimation, particularly when combined with additional sequenced single nucleotide polymorphism (SNP) loci, as in the ForenSeq DNA Signature Prep kit.
View Article and Find Full Text PDFRNA Metabolism and the Role of Small RNAs in Regulating Multiple Aspects of RNA Metabolism.
Noncoding RNA
December 2024
Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
RNA metabolism is focused on RNA molecules and encompasses all the crucial processes an RNA molecule may or will undergo throughout its life cycle. It is an essential cellular process that allows all cells to function effectively. The transcriptomic landscape of a cell is shaped by the processes such as RNA biosynthesis, maturation (RNA processing, folding, and modification), intra- and inter-cellular transport, transcriptional and post-transcriptional regulation, modification, catabolic decay, and retrograde signaling, all of which are interconnected and are essential for cellular RNA homeostasis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!