Eosinophil granulocyte plays a crucial role in the pathogenesis of allergic and non-allergic upper and lower respiratory tract diseases. A number of diseases and syndromes of nonallergic mechanisms (non IgE mediated) with nose and sinus symptoms and the presence of eosinophilic cells have been described in the recent decade. The paper focuses on the discussion of the symptomatology and classification of such cases.
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