One hundred patients were examined in periods of one to 30 years after subtotal resection of the large intestine with the formation of an ileorectal or ileo-sigmoid anastomosis for diffuse polyposis with prevalence of proliferative processes. A malignant tumor developed in the preserved distal parts of the large intestine during this period in 19 (19%) persons. Such factors as the sex, age, duration of the postoperative follow-up period, the presence of a malignant tumor in the removed part, and the length of the functioning segment of the large intestine had no essential effect on the frequency of carcinoma. The presence of any number of polyps in the remaining part of the large intestine at the moment of the surgical intervention was the principal precondition for carcinoma development. The absence of polyps in it is a favorable factor for the survival of the operated on patients; in none of them did a malignant tumor develop in the preserved segment of the large intestine.

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