The work analyses the results of late-term follow-up of 525 patients who underwent selective proximal vagotomy (SPV) in different variants. The results were gained on the basis of long-standing follow-up with the use of the complex dispensary method. The frequency of peptic ulcer recurrences after SPV was 10%. The main causes of the recurrences were: incomplete vagotomy of the parietal cell zone and inadequate selection of patients for this intervention. Finally, the authors demonstrate the clinico-pathogenetical variants of the course of peptic ulcer when SPV cannot correct the existing disorders and the therapeutic effect of the operation is doubtful. All the aforesaid dictates the need for specialization of surgeons-gastroenterologist who are engaged in this problem and for strict determination of the indications for SPV.

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