Background: Thorough understanding of the morphometric parameters of the lumbar pedicles is essential for transpedicular screw fixation. The purpose of this study is to establish a database for proper spinal instrumentations in Chinese patients.
Methods: A total of 764 pedicles (L2-S1) were measured from spinal computed tomography (CT) of 100 Chinese volunteers. Parameters related to transpedicular fixation include pedicle width (PW), pedicle transverse angle (PTA), pedicle angle measured from the entry point of Roy-Camille through the midpoint of the pedicle (PPA), screw insertion depths to the anterior cortex from the entry point of Roy-Camille along the line parallel to the midsagittal line (PPLP) and from the entry point of Magerl along the pedicle axis (PPLS).
Results: The mean age of the volunteers was 46.2 years. The average PWs from L2 to S1 were: 0.85 +/- 0.15 cm for L2, 0.92 +/- 0.22 cm for L3, 1.19 +/- 0.24 cm for L4, 1.70 +/- 0.28 cm for L5 and 2.31 +/- 0.35 cm for S1. The average PTAs from L2 to S1 were: 13.9 degrees +/- 4.9 degrees for L2, 13.4 degrees +/- 5.1 degrees for L3, 16.2 degrees +/- 5.9 degrees for L4, 27.8 degrees +/- 7.2 degrees for L5 and 44.0 degrees +/- 8.4 degrees for S1. The average PPAs from L2 to S1 were: 5.3 degrees +/- 2.4 degrees for L2, 6.3 degrees +/- 2.2 degrees for L3, 7.2 degrees +/- 2.5 degrees for L4, 10.1 degrees +/- 3.6 degrees for L5 and 17.0 degrees +/- 4.8 degrees for S1. The average PPLPs from L2 to S1 were: 5.64 +/- 0.82 cm for L2, 5.05 +/- 0.62 cm for L3, 4.99 +/- 0.89 cm for L4, 4.42 +/- 0.77 cm for L5 and 4.23 +/- 0.72 cm for S1. The average PPLSs from L2 to S1 were: 5.75 +/- 0.72 cm for L2, 5.24 +/- 0.75 cm for L3, 5.27 +/- 0.84 cm for L4, 4.88 +/- 0.72 cm for L5 and 4.99 +/- 0.72 cm for S1.
Conclusions: Transpedicular screw fixation should be tailored on individual basis. Though variation exists, no sufficient evidence can be found to suggest major morphometric differences of the Chinese lumbar pedicles from the studies in the English literature.
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J Med Internet Res
January 2025
Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Background: Primary intracranial germ cell tumors (iGCTs) are highly malignant brain tumors that predominantly occur in children and adolescents, with an incidence rate ranking third among primary brain tumors in East Asia (8%-15%). Due to their insidious onset and impact on critical functional areas of the brain, these tumors often result in irreversible abnormalities in growth and development, as well as cognitive and motor impairments in affected children. Therefore, early diagnosis through advanced screening techniques is vital for improving patient outcomes and quality of life.
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November 2024
Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Background And Objectives: Accurate intraoperative assessment of coronal alignment is critical to achieving favorable clinical outcomes in adult spinal deformity surgery. However, surgical positioning creates challenges in predicting standing coronal alignment. Gravity-based plumblines require an upright posture and are not possible intraoperatively.
View Article and Find Full Text PDFCardiol Rev
January 2025
From the Department of Neurological Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
Endosaccular flow disruption has emerged as a transformative approach for treating wide-neck intracranial aneurysms, which are characterized by neck diameters exceeding 4 millimeters or dome-to-neck ratios below 2. This review examines the technical specifications and clinical outcomes of major endosaccular devices, including the Woven EndoBridge (WEB) device, the Artisse embolization device, the Medina embolization device, the neck bridging device for bifurcation aneurysms, the polycarbonate urethane membrane-assisted device, the Galaxy saccular endovascular aneurysm lattice, and the Contour Neurovascular System. Analysis of pivotal trials reveals varying degrees of efficacy and safety across platforms.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Objective: This study aims to construct a training course and quality evaluation index system for chronic disease Medication Therapy Management service (MTMs) that is suitable for China's national conditions. It seeks to provide tools and a scientific foundation for assessing the quality of MTMs training.
Methods: Drawing from domestic and international literature and combining with the practice of chronic disease medication management by Chinese pharmacists, a preliminary framework for the evaluation index system was established.
PLoS One
January 2025
School of Communication Sciences & Disorders, University of Memphis, Memphis, Tennessee, United States of America.
We aimed to test whether hearing speech in phonetic categories (as opposed to a continuous/gradient fashion) affords benefits to "cocktail party" speech perception. We measured speech perception performance (recognition, localization, and source monitoring) in a simulated 3D cocktail party environment. We manipulated task difficulty by varying the number of additional maskers presented at other spatial locations in the horizontal soundfield (1-4 talkers) and via forward vs.
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