Immunological disorders due to fall of T-lymphocytes ratio were established while IgA and IgM levels were slightly increased. B-lymphocytes ratio demonstrated tendency to normalization 6 years after irradiation.
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J Exp Biol
January 2025
Grupo de Ecología Fisiológica y del Comportamiento. Instituto de Investigaciones Marinas y Costeras (IIMyC). CONICET - Universidad Nacional de Mar del Plata, Argentina.
Animal thermoregulation may have significant costs and compete directly or indirectly with other energetically demanding processes, such as immune function. Although the subterranean environment is characterized by thermally-stable conditions, small changes in ambient temperature could be critical in shaping immunity. However, little is known about the effects of ambient temperature, in naturally varying ranges, on immunity of wild species.
View Article and Find Full Text PDFCurr Opin Organ Transplant
January 2025
Division of Nephrology, Virginia Commonwealth University, Richmond, Virginia, USA.
Purpose Of The Review: Calcineurin inhibitors (CNIs) are central to immunosuppression in kidney transplantation (KT), improving short-term outcomes but falling short in enhancing long-term outcomes due to cardiovascular, metabolic, and renal complications. Belatacept, an FDA-approved costimulation blocker, offers a less toxic alternative to CNIs but is limited by its intravenous administration and reduced efficacy in high-immunological-risk patients.
Recent Findings: Emerging therapies target more specific pathways to improve efficacy and accessibility.
Front Oncol
December 2024
Gynecologic Oncology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Background: Ovarian cancer (OC) represents a common neoplasm within the female reproductive tract. The prognosis for patients diagnosed at advanced stages is unfavorable, primarily attributable to the absence of reliable screening markers for early detection. An elevated neutrophil-to-lymphocyte ratio (NLR) serves as an indicator of host inflammatory response and has been linked to poorer overall survival (OS) across various cancer types; however, its examination in OC remains limited.
View Article and Find Full Text PDFInt J Dev Disabil
May 2023
Department of Child and Adolescent Psychiatry, Ordu University Faculty of Medicine, Ordu, Turkey.
Inflammation is thought to play a role in the etiopathogenesis of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). Procalcitonin (PCT) is an inflammatory biomarker released by thyroid parafollicular cells. CRP is systemic biomarker of inflammation.
View Article and Find Full Text PDFFront Neurol
January 2025
School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Background: The predictive role of the lymphocyte-associated inflammation index in post-stroke cognitive impairment (PSCI) remains controversial. Therefore, we performed an updated meta-analysis to update the evidence.
Methods: This meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
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