The authors performed morphometric section studies of the peripheral nerves of 25 human fetuses of 17-26 week development. The purpose of the study was determination of the technical possibility of using revascularized nerves of the human fetus as grafts for replacement of post-traumatic defects in the peripheral nerves. The peripheral nerves of the upper limbs of fetuses of the indicated developmental periods were found to be formed morphologically. The results of morphometric study showed that it is technically possible to obtain the median, ulnar, and radial nerves on a vascular pedicle. The length and diameter of the vessels of the vascular pedicle of the upper limb peripheral nerves allow revascularization of the brephograft to be accomplished by means of microsurgical techniques.
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Bioelectromagnetics
January 2025
Department of Electrical Engineering and ITEMS, University of Southern California, Los Angeles, California, USA.
As the clinical applicability of peripheral nerve stimulation (PNS) expands, the need for PNS-specific safety criteria becomes pressing. This study addresses this need, utilizing a novel machine learning and computational bio-electromagnetics modeling platform to establish a safety criterion that captures the effects of fields and currents induced on axons. Our approach is comprised of three steps: experimentation, model creation, and predictive simulation.
View Article and Find Full Text PDFCell Adh Migr
December 2025
Department of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Peripheral nerve injury repair has always been a research concern of scientists. At the tissue level, axonal regeneration has become a research spotlight in peripheral nerve repair. Through transplantation of autologous nerve grafts or other emerging biomaterials functional recovery after facial nerve injury is not ideal in clinical scenarios.
View Article and Find Full Text PDFCureus
December 2024
Department of Interventional Neuroradiology, University Hospital of Patras, Patras, GRC.
In this case, we present the case of a 74-year-old female patient who visited the University Hospital of Patras, Greece, because of a 10-day history of earache and discharge in the left ear. Concurrently, the patient exhibited ipsilateral peripheral facial nerve palsy. We also observed vesicular eruption at the auricle and the external auditory canal (EAC) of the left ear.
View Article and Find Full Text PDFBiomed Opt Express
January 2025
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
Abnormal corneal nerve function and associated disease is a significant public health concern. It is associated with prevalent ocular surface diseases, including dry eye disease. Corneal nerve dysfunction is also a common side effect of refractive surgeries, as well as a symptom of diseases that cause peripheral neuropathies.
View Article and Find Full Text PDFNarra J
December 2024
Department of Clinical Pathology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Obesity and retinal microvasculature dysfunction are linked and impact visual acuity. The aim of this study was to determine the relationship between the HOMA-IR score and the presence of vascular dysfunction (capillary perfusion and flux index) of the optic nerve head (ONH) of the retina in obese patients and to determine its diagnostic performance to predict vascular dysfunction. A case-control study was conducted in 2022 involving individuals from obese and non-obese groups.
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