AI Article Synopsis
- The study focused on 56 patients with severe angina pectoris who were treated with gravitation plasmapheresis due to ineffective conservative therapy.
- The researchers measured platelet aggregation and blood viscosity before treatment and on subsequent days to understand their roles in predicting patient outcomes.
- Results indicated that higher blood viscosity and platelet aggregation were linked to better clinical improvement, while lower levels did not support stabilization in patients with progressive angina.
Article Abstract
The study was undertaken to examine 56 patients (mean age 54.9 +/- 1.1 years) who had functional class III (n = 12), IV (n = 32), and unstable (n = 12) angina pectoris. Due to inefficacy of conservative therapy, all the patients underwent gravitation plasmapheresis (GPA). The parameters of induced platelet aggregation were examined by the Born-O'Brien method and blood viscosity on a rotor viscometer before, immediately and on days 1 and 3 after GPA. It was found that the baseline blood viscosity and platelet aggregation should be known to predict the natural history of angina in the following 1-3 days after GPA. There was a pronounced positive clinical effect in higher blood viscosity and platelet aggregation. An improvement in the clinical course of the disease and its stabilization were not observed in the baseline lower blood viscosity and platelet in patients with progressive angina.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Commentary: Heart-brain interaction in cardiogenic dementia: pathophysiology and therapeutic potential.
Front Cardiovasc Med
January 2025
School of Health and Medical Science, University of Southern Queensland, Toowoomba, QLD, Australia.
Characteristics of transition to turbulence in a healthy thoracic aorta using large eddy simulation.
Sci Rep
January 2025
University of Ulsan, 93 Daehak-ro, Nam-gu, Ulsan, 680-749, Republic of Korea.
This study employed large eddy simulation (LES) with the wall-adapting local eddy-viscosity (WALE) model to investigate transitional flow characteristics in an idealized model of a healthy thoracic aorta. The OpenFOAM solver pimpleFoam was used to simulate blood flow as an incompressible Newtonian fluid, with the aortic walls treated as rigid boundaries. Simulations were conducted for 30 cardiac cycles and ensemble averaging was employed to ensure statistically reliable results.
View Article and Find Full Text PDFEffects of laminarin and ferulic acid on pasting, rheology, freeze-thaw stability and in vitro digestion of cassava starch.
Int J Biol Macromol
January 2025
College of Tourism and Cuisine, Yangzhou University, Yangzhou 225127, China. Electronic address:
This study aimed to investigate the effects of laminarin (LA) and ferulic acid (FA) on the gelatinization, rheological properties, freeze-thaw stability, and digestibility of cassava starch (CS). The results indicated that LA increased the peak viscosity, trough viscosity, final viscosity, storage modulus, and loss modulus of CS, while decreasing the breakdown viscosity. Conversely, FA exerted opposite effects.
View Article and Find Full Text PDFHemorrhagic Stroke in a 24-Year-Old Male With Polycythemia Vera: A Case Report and Literature Review.
Cureus
December 2024
Neurology, St. Luke's Medical Center, Quezon City, PHL.
Stroke is the second leading cause of death worldwide, according to the latest report by the World Health Organization (WHO). Intracerebral hemorrhage comprises 20-25% of the stroke in the young, with incidence rates of three to six in 100,000 people per year. One of the most common and important causes of hemorrhagic stroke in the general population is hypertension.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!